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Shedding Light on Vitamin D and Integrative OncologySteiner Medical and Therapeutic Center, Phoenixville, Pennsylvania, isc{at}steinermed.com Studies show an important relationship between vitamin D and malignancies, both in prevention and treatment. The extraskeletal actions of vitamin D relevant to oncology include being proapoptotic, antimetastatic, antiangiogenic, antiinflammatory, prodifferentiating, and immunomodulating. Widespread and severe vitamin D deficiencies exist worldwide. Decreased sun exposure, caused by lifestyle changes, as well as fear of skin cancers, is the main cause of these deficiencies. Recommended daily oral intakes, as well as suggested blood levels, are below optimal levels suggested by studies. Improvement in vitamin D status, through lifestyle changes and supplementation, can be of profound benefit regarding the occurrence and mortality of malignancies.
Key Words: vitamin D 25-OH vitamin D 1,25-OH vitamin D malignancies vitamin D deficiency vitamin D status and prognosis of malignancies melatonin melanoma circadian rhythm of light and darkness prostate cancer
This version was published on June
1, 2008 Integrative Cancer Therapies, Vol. 7, No. 2,
81-89 (2008) This article has been cited by other articles:
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