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Integrative Cancer Therapies, Vol. 5, No. 4, 391-394 (2006)
DOI: 10.1177/1534735406295311
© 2006 SAGE Publications

Case Report of a Pituitary Macroadenoma Treated With Artemether

Narendra P. Singh, MBBS, MS

Department of Bioengineering, Box 355061, University of Washington, Seattle, WA 98195. narendra{at}u.washington.edu

Vijay Kumar Panwar, MBBS

Primary Health Center, Jaroda, Muzafarnagar (U.P.), India.

Introduction: This report describes the case of a male patient with pituitary macroadenoma treated with the artemisinin analog artemether. Patient and Methods: A 75 year-old male patient presented with vision, hearing, and locomotion-related problems. Artemether was administered orally to the patient over a period of 12 months. Results: Although the tumor remained consistent in size, CT scan shows a reduction in its density, and clinically, the related symptoms and signs resolved significantly as therapy progressed. Discussion: Overall, the artemether treatment was beneficial in improving the patient's quality of life. Artemether and other artemisinin analogs offer promise for cancer therapy.

Key Words: artemether • artemisinin • pituitary gland • microadenoma • cancer • apoptosis


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